Johanna II was born as the daughter of King Charles III of Naples and Margaret of Durazzo. Johanna was the eldest daughter of Duke Charles of Calabria and Mary of Valois, daughter of Count Charles of Valois. In the autumn of 1401, at the age of 28, Johanna married Duke William of Inner Austria. In early 1415 Johanna became the betrothed of Johan, son of King Ferdinand I of Aragon and 25 years younger than her. Isabella of Aragon (October 2, 1470 – February 11, 1524) was a princess of Naples, granddaughter of Ferdinand I of Naples and daughter of Alfonso II of Naples and his wife Ippolita Maria Sforza (1446-1484). From 1489 to 1494 Isabella was Countess of Milan, from 1499 to 1524 Countess of Bari and Princess of Rossano. Isabella survived her son, who died in 1512 when he fell from his horse, and also her daughter Ipolitta. In revenge, Jacob had Johanna's lover Apolo killed and forced her to give him the title of king. Johanna, however, refused to accept the Pope's ambitious proposals and enlisted the help of the powerful King Alfonso V of Aragon, who was named heir to the Kingdom of Naples in return.

Shortly afterwards, the relationship between Johanna and the feudal lord of the kingdom of Naples, Pope Martin V, deteriorated, because she had followed Caracciolo's advice to refuse the pope economic aid to build a papal army. The relationship between the two clubs is described as Ezeli Rakip, Ebedi Dost (Eternal Adversary, Friend Forever) and Zıt Kardeşler (Opposing Brothers). He always treated Althea like a boy, and was her only close friend. Joanna I of Naples (circa 1326 – Muro Lucano, 12 May 1382) was Queen of Naples and Countess of Provence from 1343 to 1381, Princess of Achaea from 1373 to 1381 and titled Queen of Jerusalem and Sicily. On October 28, 1419, Johanna was crowned Queen of Naples and Sicily. In 1137 Roger II of Sicily, of the House of Hauteville, was able to incorporate the city and the duchy into his kingdom of Sicily.

The Duchy of Naples (Ducatus Neapolitanus) was a de facto independent duchy in southern Italy from the 9th to the 12th century with the city of Naples as its center. His uncle, Ludovico Sforza, america jersey acted as regent in place of the young duke but soon seized power and became de facto ruler of Milan. Gian Galeazzo succeeded his father and became Duke of Milan. Charles Robert's father, Charles Martel of Anjou, was in fact an older brother of Robert of Naples. Her father was the son of King Robert of Naples, heir to the throne of Naples, but died before his father in 1328. However, this inheritance arrangement was controversial, because King Charles I Robert of Hungary asserted his claims to the Neapolitan succession. To defuse the emerging conflict, Johanna was married off on September 28, 1333 to her cousin Andreas, a son of King Charles I Robert of Hungary. Normally, Charles Robert should have become king of Naples after the death of his grandfather King Charles II of Naples in 1309, but his uncle Robert was able to have himself proclaimed king with the support of the pope, while the still young Charles Robert settled in Hungary found.

René I, the younger brother of the late Louis III of Anjou, succeeded Johanna as King of Naples. After the death of her grandfather, Johanna became Queen of Naples and Countess of Provence in 1343. In 1330 Johanna was named by her grandfather as his heir and in 1333 she was given the title of Duchess of Calabria. However, the nobility in Naples revolted and in 1416 Johanna was released. There she met Louis III of Anjou, whom Johanna appointed as the new heir to Naples. After Alfonso V arrived in Naples in July 1421, Louis III of Anjou soon lost the pope's support and Joanna was able to remain Queen of Naples. In revenge, the Pope decided to support Louis III of Anjou, who was a pretender to the throne of Naples. After Louis conquered Campania in 1420, the pope had both parties convened in an attempt to take personal advantage of Johanna's threat. Lodewijk and Johanna succeeded in driving Alfonso V out of Naples and she returned to Naples in April 1424.